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2013 Mark W. Allam Lecture

Sponsored by
ACVS Industry Partner

The Microcirculation: A Trigger and Target in Inflammation and Ischemia-Reperfusion Injury

D. Neil Granger, PhD
Boyd Professor and Head
Department of Molecular and Cellular Physiology
LSU Health Sciences Center
Shreveport, LA

The lecture will focus on the microcirculation and its responses and contributions to acute and chronic inflammatory conditions, including ischemia-reperfusion injury. Dr. Granger will also address how risk factors for cardiovascular disease can influence the intensity and underlying mechanisms of microvascular dysfunction in tissues exposed to ischemia and reperfusion.

D. Neil Granger, PhD, is the Boyd Professor and Head of the Department of Molecular and Cellular Physiology at LSU Health Sciences Center. He is an author of over 500 articles in peer-review journals, over 100 book chapters, and the author/editor of six books. Granger serves on many editorial boards, including the Heart & Circulation, GI & Liver, and Cell sections of the American Journal of Physiology and multiple journals, including Circulation Research, Microcirculation, Shock, Pathophysiology, Free Radical Biology & Medicine, Lymphatic Research and Biology, and Nitric Oxide Biology. He recently served on the Council of the Association of Chairs of Departments of Physiology (2003–2005), and presently serves on the Board of Directors of the Federation of American Societies of Experimental Biology (FASEB). Granger is designated as a Highly Cited Investigator (top 1 % of cited scientists) by the Institute for Scientific Information.

Born in Erath, LA, he attended the University of Southwestern Louisiana, earning a BS in microbiology in 1973. He went on to receive his doctorate in physiology and biophysics with Aubrey Taylor at the University of Mississippi Medical Center in 1977. He served on the faculty in the Department of Physiology at the University of South Alabama from 1977 to 1986, and then assumed his present position as department head at the LSU Health Sciences Center, where he has also served as the Associate Dean for Research (1993–2001).

Granger has devoted his life to the pursuit of research and publishing. Prior to his current publishing commitments, Granger served on the editorial boards of NIPS, Gastroenterology, Digestive Diseases & Sciences, Journal of Critical Care, and Microvascular Research publications. In addition, he served as Associate Editor of the American Journal of Physiology: GI & Liver (1985–1991), Editor-in-Chief of Microcirculation (1999–2003), and Regional Editor for the Americas of Pathophysiology (2000–2007).

Granger was a member of the Clinical Sciences-2 (1983–1986), Cardiovascular & Renal (1987–1991), and General Medicine-A2 (1992-1996) Study Sections, and presently serves on the Gastrointestinal Mucosal Pathobiology Study Section of the National Institutes of Health. He also committed time to several peer review panels and policy committees for the American Heart Association, the Research Committee of the American Gastroenterological Association, and the Physiology Test Committee of the National Board of Medical Examiners (1988–1991). Granger has served on the Council of the Microcirculatory Society (1982–1985) and as its President in 1991–1992. He was elected to the Council of the American Physiological Society (1993–96) and served as its President in 2004–2005.

Granger has received several awards and honors for his research, including the APS Bowditch Award, the Distinguished Research Award from the GI Section of the APS, the Landis Award from the Microcirculatory Society, the Laerdal Award from the Society for Critical Care Medicine, the McKenna Memorial Award from the Canadian Association of Gastroenterology, the Dolph Adams Award from the Society for Leukocyte Biology, and the Career of Distinction Award from the Oxygen Society.

The Mark W. Allam Lecture is named for the late Dean Emeritus of the School of Veterinary Medicine, University of Pennsylvania. Dr. Allam was a co-founder of the American College of Veterinary Medicine. He was an avid proponent of the concept of “one medicine” – the idea that the similarities between human and animal medicine are great and that these two fields can benefit considerable from the discoveries made in each field. The Lecture was instituted to foster this concept and has been given annually since 1972.

View past Mark W. Allam Lectures